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Courses in Chemistry (CHE)

Chemistry Placement Examination. Students who enroll in Chemistry 2A, 2AH or Workload Chemistry 41C must achieve the appropriate score on the Chemistry Placement Exam. In addition to the Chemistry Placement Exam, students are also required to pass the Mathematics Placement Exam with a satisfactory score appropriate to the Chemistry course they have placed into. See the Department of Chemistry website well in advance of enrolling for details. Students who do not meet the examination requirements of both exams will be administratively dropped from these Chemistry courses.

The Student Academic Success Center (SASC) provides review materials, workshops, drop-in and group tutoring, and additional resources. Chemistry Graduate Students Tutors are also listed on the Department of Chemistry website.

Lower Division Courses

2A. General Chemistry (5)

Lecture—3 hours; laboratory/discussion—4 hours. Prerequisite: High school chemistry and physics strongly recommended; satisfactory score on diagnostic examinations. Periodic table, stoichiometry, chemical equations, physical properties and kinetic theory of gases, atomic and molecular structure and chemical bonding. Laboratory experiments in stoichiometric relations, properties and collection of gases, atomic spectroscopy, and introductory quantitative analysis. Only 3 units of credit allowed to students who have completed course 9. GE credit: SciEng | QL, SE.—I, II. (I, II.)

2AH. Honors General Chemistry (5)

Lecture—3 hours; laboratory/discussion—4 hours. Prerequisite: High school chemistry and physics; satisfactory score on diagnostic examinations; Mathematics 21A (may be taken concurrently) or consent of instructor. Limited enrollment course with a more rigorous treatment of material covered in course 2A. Students completing course 2AH can continue with course 2BH or 2B.—I. (I.)

2B. General Chemistry (5)

Lecture—3 hours; laboratory/discussion—4 hours. Prerequisite: course 2A or 2AH. Continuation of course 2A. Condensed phases and intermolecular forces, chemical thermodynamics, chemical equilibria, acids and bases, solubility. Laboratory experiments in thermochemistry, equilibria, and quantitative analysis using volumetric methods. GE credit: SciEng | QL, SE.—II, III. (II, III.)

2BH. Honors General Chemistry (5)

Lecture—3 hours; laboratory/discussion—4 hours. Prerequisite: course 2A with consent of instructor or course 2AH with a grade of C or better; and Mathematics 21B (maybe taken concurrently) or consent of instructor. Limited enrollment course with a more rigorous treatment of material covered in course 2B. Students completing course 2BH can continue with course 2CH or 2C.—II. (II.)

2C. General Chemistry (5)

Lecture—3 hours; laboratory/discussion—4 hours. Prerequisite: course 2B or 2BH. Continuation of course 2B. Kinetics, electrochemistry, spectroscopy, structure and bonding in transition metal compounds, application of principles to chemical reactions. Laboratory experiments in selected analytical methods and syntheses. GE credit: SciEng | QL, SE.—I, III. (I, III.)

2CH. Honors General Chemistry (5)

Lecture—3 hours; laboratory—6 hours. Prerequisite: course 2B with consent of instructor or course 2BH with a grade of C or better; and Mathematics 21C (maybe taken concurrently) or consent of instructor. Limited enrollment course with a more rigorous treatment of material covered in course 2C.—III. (III.)

8A. Organic Chemistry: Brief Course (2)

Lecture—2 hours. Prerequisite: course 2B with a grade of C– or higher. With course 8B, an introduction to the nomenclature, structure, chemistry, and reaction mechanisms of organic compounds. Intended for students majoring in areas other than organic chemistry.—I, III. (I, III.)

8B. Organic Chemistry: Brief Course (4)

Lecture—3 hours; laboratory—3 hours. Prerequisite: course 8A or 118A. Continuation of course 8A. Laboratory concerned primarily with organic laboratory techniques and the chemistry of the common classes of organic compounds.—I, II. (I, II.)

10. Concepts of Chemistry (4)

Lecture—4 hours. A survey of basic concepts and contemporary applications of chemistry. Designed for non-science majors and not as preparation for Chemistry 2A. Course Not open for credit to students who have had Chemistry 2A; but students with credit for course 10 may take Chemistry 2A for full credit. GE credit: SciEng, Wrt | SE, SL.—I. (I.)

98. Directed Group Study (1-5)

Prerequisite: consent of instructor. Primarily for lower division students. (P/NP grading only.)

99. Special Study for Undergraduates (1-5)

Prerequisite: consent of instructor. (P/NP grading only.)

Upper Division Courses

100. Environmental Water Chemistry (3)

Lecture—3 hours. Prerequisite: course 2C. Practical aspects of water chemistry in the environment, including thermodynamic relations, coordination chemistry, solubility calculations, redox reactions and rate laws. Computer modeling of the evolution in water chemistry from contact with minerals and gases.—II. (II.) Casey

104. Forensic Applications of Analytical Chemistry (3)

Lecture—2 hours; laboratory—3 hours. Prerequisite: course 2C. Theory and application of standard methods of chemical analysis to evidentiary samples. Use and evaluation of results from screening tests, FTIR, GC and GCMS to various sample types encountered in forensics.—I. (I.) Land

105. Analytical and Physical Chemical Methods (4)

Lecture—2 hours; laboratory—6 hours. Prerequisite: course 110A (may be taken concurrently) or courses 107A-107B. Fundamental theory and laboratory techniques in analytical and physical chemistry. Errors and data analysis methods. Basic electrical circuits in instruments. Advanced solution equilibria. Potentiometric analysis. Chromatographic separations. UV-visible spectroscopy. Lasers. GE credit: QL, SE.—I, III. (I, III.)

107A. Physical Chemistry for the Life Sciences (3)

Lecture—3 hours. Prerequisite: course 2C, Mathematics 16C or 21C, one year of college level physics. Physical chemistry intended for majors in the life science area. Introductory development of classical and statistical thermodynamics including equilibrium processes and solutions of both non-electrolytes and electrolytes. The thermodynamic basis of electrochemistry and membrane potentials.—I. (I.)

107B. Physical Chemistry for the Life Sciences (3)

Lecture—3 hours. Prerequisite: course 107A. Continuation of course 107A. Kinetic theory of gases and transport processes in liquids. Chemical kinetics, enzyme kinetics and theories of reaction rates. Introduction to quantum theory, atomic and molecular structure, and spectroscopy. Application to problems in the biological sciences.—II. (II.)

108. Physical Chemistry of Macromolecules (3)

Lecture—3 hours. Prerequisite: course 107B or 110C. Physical properties and characterization of macromolecules with emphasis upon those of biological interest. Structural thermodynamic, optical and transport properties of polymers in bulk and in solution. Physical characterization methods. Special topics on the properties of polyelectrolyte systems.—III. (III.)

110A. Physical Chemistry: Introduction to Quantum Mechanics (4)

Lecture—3 hours; discussion—1 hour. Prerequisite: course 2C, Mathematics 16C or 21C; one year of college physics. Introduction to the postulates and general principles of quantum mechanics. Approximations based on variational method and time independent perturbation theory. Application to harmonic oscillator, rigid rotor, one-electron and many-electron atoms, and homo-and hetero-nuclear diatomic molecules. GE credit: QL, SE.—I, III. (I, III.)

110B. Physical Chemistry: Properties of Atoms and Molecules (4)

Lecture—3 hours; discussion—1 hour. Prerequisite: course 110A. Group theory. Application of quantum mechanics to polyatomic molecules and molecular spectroscopy. Intermolecular forces and the gas, liquid and solid states. Distributions, ensembles and partition functions. Transport properties.—I, II. (I, II.)

110C. Physical Chemistry: Thermodynamics, Equilibria and Kinetics (4)

Lecture—3 hours; discussion—1 hour. Prerequisite: course 110B. Development and application of the general principles of thermodynamics and statistical thermodynamics. Chemical kinetics, rate laws for chemical reactions and reaction mechanisms.—II, III. (II, III.)

115. Instrumental Analysis (4)

Lecture—2 hours; laboratory—6 hours. Prerequisite: courses 105 and 110B (may be taken concurrently) or 107A-107B. Intermediate theory and laboratory techniques in analytical and physical chemistry. Advanced data analysis methods and goodness-of-fit criteria. Fouriertransform spectroscopic methods and instrumentation. Mass spectrometry. Electrochemistry. Liquid chromatography. GE credit: Wrt | QL, SE, WE.—I, II. (I, II.)

118A. Organic Chemistry for Health and Life Sciences (4)

Lecture—3 hours; laboratory/discussion—1.5 hours. Prerequisite: course 2C with a grade of C– or higher. The 118A, 118B, 118C series is for students planning professional school studies in health and life sciences. A rigorous, in-depth presentation of basic principles with emphasis on stereochemistry and spectroscopy and preparations and reactions of nonaromatic hydrocarbons, haloalkanes, alcohols and ethers.—I, II, III. (I, II, III.)

118B. Organic Chemistry for Health and Life Sciences (4)

Lecture—3 hours; laboratory—3 hours. Prerequisite: course 118A. Continuation of course 118A, with emphasis on spectroscopy and the preparation and reactions of aromatic hydrocarbons, organometallic compounds, aldehydes and ketones.—I, II, III. (I, II, III.)

118C. Organic Chemistry for Health and Life Sciences (4)

Lecture—3 hours; laboratory—3 hours. Prerequisite: course 118B. Continuation of course 118B, with emphasis on the preparation, reactions and identification of carboxylic acids and their derivatives, alkyl and acyl amines, ß-dicarbonyl compounds, and various classes of naturally occurring, biologically important compounds.—I, II, III. (I, II, III.)

121. Introduction to Molecular Structure and Spectra (4)

Lecture—4 hours. Prerequisite: course 110B. Modern theoretical and experimental methods used to study problems of molecular structure and bonding; emphasis on spectroscopic techniques.—III. (III.)

122. Chemistry of Nanoparticles (3)

Lecture—3 hours. Prerequisite: course 110C (may be taken concurrently). Chemical and physical aspects of inorganic nanoparticles. Topics include synthesis, structure, colloidal behavior, catalytic activity, size and shape dependency of physical properties, analytical methods and applications.—III. (III.) Osterloh

124A. Inorganic Chemistry: Fundamentals (3)

Lecture—3 hours. Prerequisite: course 2C. Symmetry, molecular geometry and structure, molecular orbital theory of bonding (polyatomic molecules and transition metals), solid state chemistry, energetics and spectroscopy of inorganic compounds.—I. (I.)

124B. Inorganic Chemistry: Main Group Elements (3)

Lecture—3 hours. Prerequisite: course 124A. Synthesis, structure and reactivity of inorganic and heteroorganic molecules containing the main group elements.—II. (II.)

124C. Inorganic Chemistry: d and f Block Elements (3)

Lecture—3 hours. Prerequisite: course 124A. Synthesis, structure and reactivity of transition metal complexes, organometallic and bioinorganic chemistry, the lanthanides and actinides.—III. (III.)

124L. Laboratory Methods in Inorganic Chemistry (2)

Laboratory—6 hours. Prerequisite: course 124B or 124C (may be taken concurrently). The preparation, purification and characterization of main group and transition metal inorganic and organometallic compounds.—III. (III.)

125. Advanced Methods in Physical Chemistry (4)

Lecture—2 hours; laboratory—6 hours. Prerequisite: course 110C (may be taken concurrently) and 115. Advanced theory and laboratory techniques in analytical and physical chemistry. Advanced spectroscopic methods. Thermodynamics. Kinetics. Chemical literature. Digital electronics and computer interfacing. Laboratory measurements and vacuum techniques. GE credit: Wrt | QL, SE, WE.—II, III. (II, III.)

128A. Organic Chemistry (3)

Lecture—3 hours. Prerequisite: course 2C with a grade of C or higher; chemistry majors should enroll in course 129A concurrently. Introduction to the basic concepts of organic chemistry with emphasis on stereochemistry and the chemistry of hydrocarbons. Designed primarily for majors in chemistry.—I, II. (I, II.)

128B. Organic Chemistry (3)

Lecture—3 hours. Prerequisite: course 128A or consent of instructor, course 129A strongly recommended; chemistry majors should enroll in course 129B concurrently. Continuation of course 128A with emphasis on aromatic and aliphatic substitution reactions, elimination reactions, and the chemistry of carbonyl compounds. Introduction to the application of spectroscopic methods to organic chemistry.—II, III. (II, III.)

128C. Organic Chemistry (3)

Lecture—3 hours. Prerequisite: course 128B, chemistry majors should enroll in course 129C concurrently. Continuation of course 128B with emphasis on enolate condensations and the chemistry of amines, phenols, and sugars; selected biologically important compounds.—I, III. (I, III.)

129A. Organic Chemistry Laboratory (2)

Lecture—1 hour; laboratory—3 hours. Prerequisite: course 2C with a grade of C or higher; course 128A (may be taken concurrently). Introduction to laboratory techniques of organic chemistry. Emphasis is on methods used for separation and purification of organic compounds.—I, II. (I, II.)

129B. Organic Chemistry Laboratory (2)

Laboratory—6 hours. Prerequisite: courses 128B (may be taken concurrently) and 129A. Continuation of course 129A. Emphasis is on methods used for synthesis and isolation of organic compounds.—II, III. (II, III.)

129C. Organic Chemistry Laboratory (2)

Laboratory—6 hours. Prerequisite: courses 128C (may be taken concurrently) and 129B. Continuation of course 129B.—I, III. (I, III.)

130A. Pharmaceutical Chemistry (3)

Lecture—3 hours. Prerequisite: course 118C or 128C. Examination of the design principles and experimental methods used in pharmaceutical and medicinal chemistry.—II. (II.)

130B. Pharmaceutical Chemistry (3)

Lecture—2 hours; lecture/laboratory—1 hours.
Prerequisite: course 130A. Continuation of course 130A with emphasis on case studies of various drugs and the use of computational methods in drug design.—III. (III.)

131. Modern Methods of Organic Synthesis (3)

Lecture—3 hours. Prerequisite: course 128C. Introduction to modern synthetic methodology in organic chemistry with emphasis on stereoselective reactions and application to multistep syntheses of organic molecules containing multifunctionality.—I. (I.)

135. Advanced Bio-organic Chemistry Laboratory (3)

Lecture—1 hour; laboratory—6 hours. Prerequisite: course 118C or 129C. Separation, purification, identification and biological evaluation of organic compounds using modern methods of synthesis, computational chemistry and instrumentation. Emphasis on pharmaceutical and medicinal substances.—III. (III.)

150. Chemistry of Natural Products (3)

Lecture—3 hours. Prerequisite; course 128C. Chemistry of terpenes, steroids, acetogenins, and alkaloids: isolation, structure determination, biosynthesis, chemical transformations, and total synthesis. GE credit: SciEng, Wrt | SE, WE.—III. (III.)

192. Internship in Chemistry (1-6)

Internship—3-18 hours. Prerequisite: upper division standing; project approval by faculty sponsor prior to enrollment. Supervised internship in chemistry; requires a final written report. May be repeated for credit for a total of 6 units. (P/NP grading only.)

194HA-194HB-194HC. Undergraduate Honors Research (2-2-2)

Independent study—2 hours. Prerequisite: open only to chemistry majors who have completed 135 units and who qualify for the honors program. Original research under the guidance of a faculty adviser, culminating in the writing of an extensive report. (Deferred grading only, pending completion of sequence.)

195. Careers in Chemistry (1)

Seminar—2 hours. Prerequisite: junior or senior standing in Chemistry. Designed to give Chemistry undergraduate students an in-depth appreciation of career opportunities with a bachelors degree in chemistry. Professional chemists (and allied professionals) describe research and provide career insights. (P/NP grading only.)—I.

197. Projects in Chemical Education (1-4)

Discussion and/or laboratory. Prerequisite: consent of instructor. Participation may include development of laboratory experiments, lecture demonstrations, autotutorial modules or assistance with laboratory sessions. May be repeated for credit for a total of 12 units. (P/NP grading only.)—I, II, III. (I, II, III.)

198. Directed Group Study (1-5)

Prerequisite: consent of instructor based upon adequate preparation in chemistry, mathematics and physics. (P/NP grading only.)

199. Special Study for Advanced Undergraduates (1-5)

Prerequisite: consent of instructor based upon adequate preparation in chemistry, mathematics, and physics. (P/NP grading only.)

Graduate Courses

201. Chemical Uses of Symmetry and Group Theory (3)

Lecture—3 hours. Prerequisite: course 124A and 110B, or consent of instructor. Symmetry elements and operations, point groups, representations of groups. Applications to molecular orbital theory, ligand field theory, molecular vibrations, and angular momentum. Crystallographic symmetry.—I. (I.)

204. Mathematical Methods in Chemistry (3)

Lecture—3 hours. Prerequisite: course 110C; graduate standing in Chemistry. Introduction to mathematical and numerical methods in chemistry. Real and complex functions. Methods of integration. Differential equations. Linear algebra and matrices. Special functions. Integral transforms. Statistics.—I. (I.)

205. Symmetry, Spectroscopy, and Structure (3)

Lecture—3 hours. Prerequisite: course 201 or the equivalent. Vibrational and rotational spectra; electronic spectra and photoelectron spectroscopy; magnetism; electron spin and nuclear quadrapole resonance spectroscopy; nuclear magnetic resonance spectroscopy; other spectroscopic methods.—II. (II.)

209. Special Topics in Physical Chemistry (3)

Lecture—3 hours. Prerequisite: courses 210A and 211A; graduate standing in Chemistry. Advanced topics in physical chemistry, biophysical chemistry or chemical physics chosen from areas of current research interest. May be repeated for credit.

210A. Quantum Chemistry: Introduction and Stationary-State Properties (3)

Lecture—3 hours. Prerequisite: course 110B and 110C or consent of instructor. Stationary-state quantum chemistry: postulates of quantum mechanics, simple solutions, central field problems and angular momenta, hydrogen atom, perturbation theory, variational theory, atoms and molecules.—II. (II.)

210B. Quantum Chemistry: Time-Dependent Systems (3)

Lecture—3 hours. Prerequisite: course 210A. Matrix mechanics and time-dependent quantum chemistry: matrix formulation of quantum mechanics, Heisenberg representation, time-dependent perturbation theory, selection rules, density matrices, and miscellaneous molecular properties.—III. (III.)

210C. Quantum Chemistry: Molecular Spectroscopy (3)

Lecture—3 hours. Prerequisite: course 210B. Molecular spectroscopy: Born-Oppenheimer approximation, rotational, vibrational and electronic spectroscopy, spin systems, and molecular photophysics.—I. (I.)

211A. Advanced Physical Chemistry: Statistical Thermodynamics (3)

Lecture—3 hours. Prerequisite: consent of instructor. Principles and applications of statistical mechanics; ensemble theory; statistical thermodynamics of gases, solids, liquids, electrolyte solutions and polymers; chemical equilibrium.—I. (I.)

211B. Statistical Mechanics (3)

Lecture—3 hours. Prerequisite: course 211A. Statistical mechanics of nonequilibrium systems, including the rigorous kinetic theory of gases, continuum mechanics transport in dense fluids, stochastic processes, brownian motion and linear response theory. Offered in alternate years.—II.

212. Chemical Dynamics (3)

Lecture—3 hours. Prerequisite: consent of instructor. Introduction to modern concepts in chemical reaction dynamics for graduate students in chemistry. Emphasis will be placed on experimental techniques as well as emerging physical models for characterizing chemical reactivity at a microscopic level. Offered in alternate years.—II.

215. Theoretical and Computational Chemistry (3)

Lecture—3 hours. Prerequisite: courses 211A and 210B or consent of instructor. Mathematics of wide utility in chemistry, computational methods for guidance or alternative to experiment, and modern formulations of chemical theory. Emphasis will vary in successive years. May be repeated for credit when topic differs. Offered in alternate years.—(III.)

216. Magnetic Resonance Spectroscopy (3)

Lecture—3 hours. Prerequisite: courses 210A, 210B (may be taken concurrently). Quantum mechanics of spin and orbital angular momentum, nuclear magnetic resonance, theory of chemical shift and multiplet structures, electron spin resonance, theory of g-tensor in organic and transition ions, spin Hamiltonians, nuclear quadrupolar resonance, spin relaxation processes. Offered in alternate years.—(III.)

217. X-Ray Structure Determination (3)

Lecture—3 hours. Prerequisite: consent of instructor. Introduction to x-ray structure determination; crystals, symmetry, diffraction geometry, sample preparation and handling, diffraction apparatus and data collection, methods of structure solution and refinement, presentation of results, text, tables and graphics, crystallographic literature.—III. (III.)

218. Macromolecules: Physical Principles (3)

Lecture—3 hours. Prerequisite: courses 110A, 110B, 110C or the equivalent. Relationship of higher order macromolecular structure to subunit composition; equilibrium properties and macromolecular dynamics; physical chemical determination of macromolecular structure. Offered in alternate years.—I.

219. Spectroscopy of Organic Compounds (4)

Lecture—3 hours; laboratory—2.5 hours. Prerequisite: course 128C or the equivalent. Identification of organic compounds and investigation of stereochemical and reaction mechanism phenomena using spectroscopic methods—principally NMR, IR and MS.—II. (II.)

219L. Laboratory in Spectroscopy of Organic Compounds (1)

Laboratory—2.5 hours. Prerequisite: course 219 (may be taken concurrently). Restricted to Chemistry graduate students only (or consent of instructor). Practical application of NMR, IR and MS techniques for organic molecules.—III. (III.)

221A-H. Special Topics in Organic Chemistry (3)

Lecture—3 hours. Selected topics of current interest in organic chemistry. Topics will vary each time the course is offered, and in general will emphasize the research interests of the staff member giving the course.—I. (I.)

222. Chemistry of Nanoparticles (3)

Lecture/discussion—3 hours. Prerequisite: course 110C or equivalent. Chemical and physical aspects of inorganic nanoparticles, including synthesis, purification, reactivity, characterization, and applications for technology. Emphasis is on problems from the current literature. Not open for credit to students who have taken course 122.—III. (III.) Osterloh

226. Principles of Transition Metal Chemistry (3)

Lecture—3 hours. Prerequisite: course 124A or the equivalent. Electronic structures, bonding, and reactivity of transition metal compounds.—I. (I.) Balch

228A. Bio-inorganic Chemistry (3)

Lecture—3 hours. Prerequisite: course 226 or consent of instructor. Defines role of inorganic chemistry in the functioning of biological systems by identifying the functions of metal ions and main group compounds in biological systems and discussing the chemistry of model and isolated biological compounds. Offered every third year.—II.

228B. Main Group Chemistry (3)

Lecture—3 hours. Prerequisite: course 226 or consent of instructor. Synthesis, physical properties, reactions and bonding of main group compounds. Discussions of concepts of electron deficiency, hypervalency, and non-classical bonding. Chemistry of the main group elements will be treated systematically. Offered every third year.—II.

228C. Solid-State Chemistry (3)

Lecture—3 hours. Prerequisite: courses 124A, 110B, 226, or the equivalent. Design and synthesis, structure and bonding of solid-state compounds; physical properties and characterization of solids; topics of current interest such as low-dimensional materials, inorganic polymers, materials for catalysis. Offered every third year.—II.

228D. Homogeneous Catalysis (3)

Lecture—3 hours. Prerequisite: course 226. Overview of homogeneous catalysis and related methods, with emphasis on kinetics, mechanisms, and applications for organic synthesis. The related methods may include cluster, colloid, phase transfer, enzymatic, heterogeneous and polymer-supported catalysis. Offered every third year.—II.

231A. Organic Synthesis: Methods and Strategies (4)

Lecture—3 hours; lecture/discussion—3 hours. Prerequisite: course 128C or equivalent. Current strategies and methods in synthetic organic chemistry. Focus on construction of carbon frameworks, control of relative and absolute stereochemistry and retrosynthetic strategies. Use of databases and molecular modeling software in multistep strategies. Only one unit of credit for students who have completed course 131. Not open for credit to students who have taken course 231.—II. (II.)

231B. Advanced Organic Synthesis (3)

Lecture—3 hours. Prerequisite: course 231A. Current strategies and methods in synthetic organic chemistry. Continuation of course 231A. Organic synthesis of complex target molecules. Stereochemical considerations and asymmetric synthesis. Organometallics for selective transformations. Carbocyclic and heterocyclic ring formation. Not open for credit to students who have taken course 231.—III. (III.)

233. Physical-Organic Chemistry (3)

Lecture—3 hours. Prerequisite: courses 128A-128B-128C and 110A-110B-110C or the equivalent. Introduction to elementary concepts in physical-organic chemistry including the application of simple numerical techniques in characterizing and modeling organic reactions.—I. (I.)

235. Organometallic Chemistry in Organic Synthesis (3)

Lecture—3 hours. Prerequisite: course 128C. Current trends in use of organometallics for organic synthesis; preparations, properties, applications, and limitations of organometallic reagents derived from transition and/or main group metals. Offered in alternate years.—(III.)

236. Chemistry of Natural Products (3)

Lecture—3 hours. Prerequisite: course 128C or the equivalent. Advanced treatment of chemistry of naturally occurring compounds isolated from a variety of sources. Topics will include isolation, structure determination, chemical transformations, total synthesis, biological activity, and biosynthesis. Biosynthetic origin will be used as a unifying theme.—II. (II.)

237. Bio-organic Chemistry (3)

Lecture—3 hours. Prerequisite: course 128C or the equivalent. Structure and function of biomolecules; molecular recognition; enzyme reaction mechanisms; design of suicide substrates for enzymes; enzyme engineering; design of artificial enzymes and application of enzymes in organic synthesis. Offered in alternate years.—(I.)

238. Introduction to Chemical Biology (3)

Lecture—3 hours. Prerequisite: course 118C or 128C, or the equivalent; course 130A & B and Biological Sciences 102, 103, & 104, or the equivalents recommended. Synthesis of complex molecules in nature. Use of biosynthetic pathways in synthesis of new chemical entities. Applications of small molecules in chemical genetics and structural biology. Solving biological problems using synthetic biomolecules.—II. (II.) Beal

240. Advanced Analytical Chemistry (3)

Lecture—3 hours. Prerequisite: courses 110A and 115 or the equivalent. Numerical treatment of experimental data; thermodynamics of electrolyte and non-electrolyte solutions; complex equilibria in aqueous and non-aqueous solutions; potentiometry and specific ion electrodes; mass transfer in liquid solutions; fundamentals of separation science, including column, gas and liquid chromatography.—I. (I.)

241A. Surface Analytical Chemistry (3)

Lecture—3 hours. Prerequisite: course 110C or the equivalent. Concepts of surfaces and interfaces: physical properties, unique chemistry and electronic effects. Focus on gas-solid interfaces, with some discussion of liquid-solid interfaces. Offered in alternate years.—I.

241B. Laser and X-ray Spectroscopy (3)

Lecture—3 hours. Prerequisite: course 110B or the equivalent. Concepts and mechanisms of light-matter interactions. Chemical applications of modern spectroscopic methods, including multiphoton spectroscopy, time-resolved laser and x-ray photolysis, and phase-contrast x-ray imaging. Offered in alternate years.—I.

241C. Mass Spectrometry (3)

Lecture—3 hours. Prerequisite: course 110C and 115 or the equivalent. Mass spectrometry and related methods with emphasis on ionization methods, mass analyzers, and detectors. Related methods may include ion-molecule reactions, unimolecular dissociation of organic and bio-organic compounds, and applications in biological and environmental analysis. Offered in alternate years.—II.

241D. Electroanalytical Chemistry (3)

Lecture—3 hours. Prerequisite: course 110C and 115 or the equivalent. Electroanalytical chemistry with consideration of mass transfer and electrode kinetics for polarizable electrodes. Current-potential curves for a variety of conditions, including both potentiostatic and galvanostatic control, and their application in chemical analysis. Offered in alternate years.—II.

241E. Microscopy and Imaging Techniques (3)

Lecture—3 hours. Prerequisite: course 110C and 115 or the equivalent. Introduction to modern microscopy and imaging techniques: scanning tunneling, atomic force, far-field optical, fluorescence, scanning near-field optical, and scanning electron microscopy. Application to nanoscience and analytical and bioanalytical chemistry. Some laboratory demonstrations. Offered in alternate years.—II.

261. Current Topics in Chemical Research (2)

Lecture—2 hours. Prerequisite: graduate standing in Chemistry or consent of instructor. Designed to help chemistry graduate students develop and maintain familiarity with the current and past literature in their immediate field of research and related areas. May be repeated for credit when topics differ.—I, II, III. (I, II, III.)

263. Introduction to Chemical Research Methodology (3)

Laboratory/discussion—9 hours. Prerequisite: course 293 and graduate student standing in Chemistry; consent of instructor. Introduction to identification, formulation, and solution of meaningful scientific problems including experimental design and/or theoretical analyses of new and prevailing techniques, theories and hypotheses. May be repeated for credit when topic differs. (S/U grading only.)—I, II, III. (I, II, III.)

264. Advanced Chemical Research Methodology (6)

Laboratory/discussion—18 hours. Prerequisite: course 263 or consent of instructor. Applications of the methodology developed in Chemistry 263 to experimental and theoretical studies. Advanced methods of interpretation of results are developed. Includes the preparation of manuscripts for publication. May be repeated for credit when topic differs. (S/U grading only.)—I, II, III. (I, II, III.)

280. Seminar in Ethics for Scientists (2)

Seminar—2 hours. Prerequisite: graduate standing in any department of Science or Engineering. Studies of topical and historical issues in the ethics of science, possibly including issues such as proper authorship, peer review, fraud, plagiarism, responsible collaboration, and conflict of interest. Limited enrollment. (Same course as Engineering Chemical and Materials Science 280 and Physics 280.) (S/U grading only.)—III. (III.)

290. Seminar (2)

Seminar—2 hours. Prerequisite: consent of instructor. (S/U grading only.)—I, II, III. (I, II, III.)

293. Introduction to Chemistry Research (1)

Discussion—2 hours. Designed for incoming graduate students preparing for higher degrees in chemistry. Group and individual discussion of research activities in the Department and research topic selection. (S/U grading only.)—I. (I.)

294. Presentation of Chemistry Research (1)

Seminar—2 hours. Prerequisite: graduate standing; restricted to graduate students in Chemistry who have not yet given their departmental presentation. Introduces first- and second-year Chemistry graduate students to the process of giving an effective research presentation. Advanced Ph.D. students give formal seminars describing the design and execution of their research projects. May be repeated three times for credit. (S/U grading only.)—II, III. (II, III.)

295. Careers in Chemistry (1)

Seminar—2 hours. Prerequisite: graduate standing in Chemistry. Designed to give Chemistry graduate students an in-depth appreciation of career opportunities with a M.S. or Ph.D. degree in chemistry. Professional chemists (and allied professionals) give seminars describing both research and career insights. May be repeated for credit 3 times. (S/U grading only.)—I.

296. Research in Pharmaceutical Chemistry (6)

Laboratory—18 hours. Prerequisite: courses 130A and 130B, 135, and 233 (may be taken concurrently). Restricted to students in the Integrated B.S./M.S. Program in Chemistry. The laboratory provides qualified graduate students with the opportunity to pursue original investigation in Pharmaceutical Chemistry and allied fields in order to fulfill the letter-graded research requirement of the Integrated B.S./M.S. Program in Chemistry (Pharmaceutical Chemistry Emphasis). May be repeated three times for credit.—I, II, III. (I, II, III.)

298. Group Study (1-5)

299. Research (1-12)

The laboratory is open to qualified graduate students who wish to pursue original investigation. Students wishing to enroll should communicate with the department well in advance of the quarter in which the work is to be undertaken. (S/U grading only.)

Professional Courses

390. Methods of Teaching Chemistry (2)

Lecture—1 hour; discussion—1 hour. Prerequisite: graduate student standing in Chemistry and consent of instructor. Practical experience in methods and problems of teaching chemistry. Includes analyses of texts and supporting material, discussion of teaching techniques, preparing for and conducting of discussion sessions and student laboratories. Participation in the teaching program required for Ph.D. in chemistry. May be repeated for credit. (S/U grading only.)—I, II, III. (I, II, III.)

392. Advanced Methods of Teaching Chemistry (2)

Lecture—2 hours. Prerequisite: course 390. Advanced topics in teaching chemistry. Analysis and discussion of curricular design, curricula materials, teaching methods and evaluation. For students who are planning a career in teaching chemistry. (P/NP grading only.)—III. (III.)

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Updated: January 29, 2013 3:25 PM