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Courses in Genetics (GGG)

Graduate

201A. Advanced Genetic Analysis (5)

Lecture/discussion—5 hours. Prerequisite: Biological Sciences 101, Statistics 100 or the equivalent, graduate standing. Fundamentals of genetic analysis and chromosome structure using model organisms including mutation, transmission, complementation, suppression, and enhancement as well as epigenetic phenomena at the whole organism and molecular levels.—F. (F.) 

201B. Genomics (5)

Lecture—3 hours; discussion—2 hours. Prerequisite: course 201A, course 201C or equivalents that provide a basic understanding of genetics and molecular biology. Class limited to 40 students; priority to Genetics Graduate Group students. Prokaryotic and eukaryotic genomes. Experimental strategies and analytical challenges of modern genomics research and the theory and mechanics of data analysis. Structural, functional, and comparative genomics. Related issues in bioinformatics.—W. (W.) 

201C. Molecular Genetic Mechanisms in Disease (4)

Lecture/discussion—4 hours. Prerequisite: Biological Sciences 101 or the equivalent. Pass One restricted to graduate students in genetics, microbiology or biochemistry and molecular biology graduate groups. Exploration of how basic mechanisms of molecular biology contribute to health and disease. Diseases related to animals, plants, and microbes will highlight fundamental concepts in the assembly, function and regulation of DNA, RNA, and protein. 

201D. Quantitative and Population Genetics (5)

Lecture—5 hours. Prerequisite: course 201A or consent of instructor. Basic concepts of quantitative and population genetics including gene and genotypic frequencies, multiple factor hypothesis, phenotypic and genotypic values, heritability, selection, genetic variation, the detection of quantitative trait loci and evolution in populations. Experimental and analytical methods.—S. (S.) Famula, Ross-Ibarra

205. Molecular Genetics Laboratory (5)

Laboratory—15 hours. Prerequisite: Biological Sciences 101 (may be taken concurrently) or the equivalent, enrolled in Genetics Graduate Group. Students will conduct experiments in molecular genetics laboratories. Individual research problems will emphasize experimental design, experience with methodologies, and data interpretation. May be repeated up to three times for credit. (S/U grading only.)—F, W, S. (F, W, S.)

210. Horizontal Gene Transfer (3)

Lecture/discussion—3 hours. Prerequisite: background in basic microbiology and genetics required; introductory course in molecular biology, biotechnology and microbial and animal/plant genetics recommended. Transfer of genes between unrelated organisms in nature. Dissemination of foreign DNA from genetically engineered organisms, including plants and animals. Mechanisms by which genes are transferred horizontally, and between kingdoms.—F. (F.) 

211. Concepts in Human Genetics and Genomics (3)

Lecture/discussion—3 hours. Prerequisite: course 201A or the equivalent; course 201B, 201C or the equivalent recommended. Pass One restricted to graduate students enrolled in the Human Genetics Focus Group; Pass Two restricted to graduate students enrolled in Genetics Graduate Group; after that, open enrollment for graduate students up to 12 students, then undergraduates. Human genomic organization; genetic structure of populations; positional cloning, application of linkage, association, and haplotypes; quantitative trait loci analyses; integrative genetic studies of gene expression; DNA repair mechanisms in genetic disease; mutation analyses; epigenetics; mitochondrial disease; gene manipulation and therapy. Offered in alternate years.—(W.)

220. Genomics and Biotechnology of Plant Improvement (3)

Lecture—3 hours. Prerequisite: Biological Sciences 101 or the equivalent. Integration of modern biotechnology and classical plant breeding including the impact of structural, comparative and functional genomics on gene discovery, characterization and exploitation. Also covers molecular markers, plant transformation, hybrid production, disease resistance, and novel output traits. (Same course as Plant Sciences 220.)—W. (W.) Neale

225. Gene Therapy (3)

Lecture/discussion—3 hours. Prerequisite: Genetics 201C, Molecular and Cellular Biology 214, or equivalent. Gene therapy from basic concepts to clinical applications. Topics include the human genome and genetic variation, genetic diseases, methods to manipulate gene expression, viral and non-viral delivery vectors, history and progress of gene therapy, case studies, and ethical issues. (Same course as Pharmacology & Toxicology 225.)—S. (S.) Anderson

250. Functional Genomics: From Bench to Bedside (3)

Lecture/discussion—3 hours. Prerequisite: course 201C, Molecular and Cellular Biology 214, or equivalent. Functional genomics (how genetic variation and epigenomics affect gene expression), with an emphasis on clinical relevance and applications. Topics include genetic variation and human disease, cancer therapeutics, and biomarker discovery. (Same course as Pharmacology & Toxicology 250.)—S. (S.) Diaz, LaSalle, Segal

290. Seminar in Evolutionary, Developmental and Population Genetics (1)

Seminar—1 hour. Topics of current interest in evolutionary, population, and developmental genetics. May be repeated for credit. (S/U grading only.) Offered in alternate years.—S. (S.) 

290A. Graduate Student Conference in Genetics (1)

Conference—1 hour. Restricted to Genetics Graduate Group students. Student-given seminars on topics in genetics, with critiques by instructor and peers. May be repeated for credit. (S/U grading only.)—F, W, S. (F, W, S.) 

291. Seminar in History of Genetics (2)

Seminar—2 hours. Prerequisite: Biological Sciences 101. The development of modern genetic theories beginning with Mendel.—F. (F.) Quiros

292. Seminar in Genomics and Epigenomics (1)

Seminar—1 hour. Topics of current interest in genomics and epigenomics. May be repeated for credit. Offered in alternate years. (S/U grading only.)—(F.) 

293. Seminar in Animal Genetics (1-3)

Seminar—1-3 hours. Prerequisite: course 201A or consent of instructor. Emphasis on recent advances in the field of animal genetics, ranging from quantitative genetics to molecular biology as it relates to animals. Offered in alternate years.—S. 

294. Seminar in Human Genetics (2)

Seminar—2 hours. Prerequisite: course 201A and consent of instructor. May be repeated for credit up to five times if topic differs. Topics of current interest in human genetics and genomics. Offered in alternate years.—W. Seldin

295. Seminar in Molecular Genetics (1-3)

Seminar—1-3 hours. Prerequisite: course 201A or consent of instructor. Topics of current interest related to the structure, modification and expression of genes. Offered in alternate years.—F. 

296. Scientific Professionalism and Integrity (2)

Lecture—1 hour; seminar—1 hour. Prerequisite: graduate standing or consent of instructor. Review of basic skills required of contemporary scientists. Topics include scientific conduct, manuscript preparation, grant writing, seminar presentations, and time management. Emphasis on responsibilities of scientists to factually and thoughtfully communicate results.—F. (F.) Yoder

297. Seminar in Plant Genetics (1-3)

Seminar—1-3 hours. Prerequisite: course 201A or consent of instructor. Current topics in plant genetics will be examined in student-conducted seminars and discussion format. The integration of molecular, organismal and population genetics to address questions in plant biology will be emphasized.—(W.) 

298. Group Study (1-5)

Prerequisite: consent of instructor. Group study of selected topics in genetics. (S/U grading only.)—F, W, S. (F, W, S.) 

299. Research (1-12)

(S/U grading only.)—F, W, S. (F, W, S.) 

Professional

300. Methods in Teaching Genetics (1-3)

Lecture/discussion. Prerequisite: graduate standing and consent of instructor. Practical experience in the methods and problems of teaching genetics. Includes analysis of texts and supporting material, discussion of teaching techniques, preparing for and conducting discussion or laboratory sections, formulating examinations under supervision of instructor. May be repeated for credit up to 3 times or 9 units if teaching in different genetics related course. (S/U grading only.)—F, W, S. (F, W, S.) 

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Updated: November 21, 2017 12:17 PM